Bronchodilator responsiveness testing in young children

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Diagnostic accuracy of bronchodilator responsiveness in wheezy children.

BACKGROUND The aim of this study was to evaluate the diagnostic accuracy of bronchodilator responsiveness for asthma in 5-10 year old children. METHODS Spirometric measurements were made in 142 children (58 wheezers) before and after 400 mug inhaled salbutamol. RESULTS On a receiver operating characteristic curve, a 9% increase in predicted forced expiratory volume in 1 second was the cut o...

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Bronchodilator responsiveness using spirometry in healthy and asthmatic preschool children.

OBJECTIVE To assess repeatability and reproducibility of spirometry measurements, and bronchodilator responsiveness (BDR), in healthy 3-6-year-old preschool children and those with asthma. DESIGN Spirometry was performed before and 20 minutes after administering either inhaled placebo (for repeatability) or 400 μg salbutamol (for BDR) on two separate occasions (reproducibility) 3-23 days apar...

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Assessment of bronchodilator responsiveness in preschool children using forced oscillations.

BACKGROUND The forced oscillation technique (FOT) requires minimal patient cooperation and is feasible in preschool children. Few data exist on respiratory function changes measured using FOT following inhaled bronchodilators (BD) in healthy young children, limiting the clinical applications of BD testing in this age group. A study was undertaken to determine the most appropriate method of quan...

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Spirometry and bronchodilator responsiveness in wheezing preschool children

Methods We carried out a retrospective analysis of incentive spirometry tests in recurrent wheezing children, aged 2-5 years, from our center, performed between September 2012 and March 2014. Lung function was assessed before and after 400 mg of inhaled salbutamol using a Jaeger spirometer v.4.65 (CareFusion). Wheezing symptoms, parental asthma, prematurity, passive smoking exposure, atopy and ...

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Bronchodilator responsiveness: interpret with caution.

Bronchodilator responsiveness (BDR) is widely considered to be a key diagnostic criterion for asthma, and is used to differentiate asthma from chronic obstructive pulmonary disease (COPD). Currently, the threshold of a 12% increase in FEV1 from baseline following inhaled salbutamol, with at least a 200 ml increase in absolute terms, is recommended as a response indicative of asthma, although re...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 2001

ISSN: 0003-9888

DOI: 10.1136/adc.84.6.525n